QoL in CD: Conclusions
•CD is associated with a diminished QoL
–Distressing
physical symptoms
–Impaired
psychological and social functioning
•Trials have shown improvements in QoL for patients treated with mesalamine, budesonide, and methotrexate
•Impact of infliximab on QoL has been well studied
–Significant
improvements in overall QoL scores and many individual
dimensions
–Improvements
observed with single and multiple infusions
•Further research is needed