Improvement in IBDQ Scores With
Methotrexate in CD

Feagan BG et al. N Engl J Med. 1995;332:292.

Higher IBDQ scores = better QoL

IBDQ Score

p<0.001 overall

p<0.001 at Week 16

0

2

4

6

16

8

10

12

14

125

150

175

200

Placebo (n=47)

MTX 25 mg/wk IM (n=94)

Weeks